Bleximenib (J&J-75276617)

AML Global MOA Video 

Sean
Rooney, PhD

Chief Medical Strategy

Yury
Stefanov, PhD

Chief Science Officer at MoA, MoD animation Department

Ivan
Konstantinov, MSc

CEO, Founder,
Art Director

Michael
Russo

Strategic Partnerships

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17+ years agency experience across multiple disciplines

30+ years life science communications

PhD in Immunology from Harvard University

Jane Coffin Childs Postdoctoral Fellowship at Rockefeller University

Former Managing Partner within HCG (an Omnicom company) and Chief Science Officer at VML Health (a WPP company)

Dean of OncU (Omnicom)
and faculty at Oncology Academy (WPP)

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Health tech startups, global agency networks

Onc/hem global launches, IMIDs, PD-1, etc.

Software & technology
solutions for Pharma

B.S. Marketing & Advertising Emerson College

Omnicom executive leadership program: Harvard led

15+ years life science communications across
multiple disciplines

PhD molecular biology

300+ animation developed
for TOP pharma companies

49 awards received, including  two from Science and National Science Foundation

16+ years life science communications across
multiple disciplines

20+ years digital communications

MSc molecular biology

Professional Biomedical Illustrator (AMI)

49 awards received, including  two from Science and National Science Foundation

All fueled by the most advanced production pipeline in the industry

15 years in hematology & oncology space 

50+

Collaboration with EHA

• Clonal hematopoiesis (CHIP): mechanisms and consequences

• The leukemic Bone Marrow niche and pathogenesis of AML

• BCL2: genetic alteration and role in lymphoid malignancies

• Mechanisms of action: CAR-T cells

• Mechanisms of action: Bispecific Abs

• Mechanisms of action: small molecules inhibitors

• The role of epigenetic mechanisms in hematological malignancies

• Techniques: NGS (TIF: PH)

• Techniques: qPCR (TIF: PH)

• Techniques: single cell genetics (TIF: pH)

• Von Willebrand factor structure and defects

• AI in hematology: AI-based digital morph. analysis

• Synthetic patients in clinical trials

• RBCs: Hb linking and releasing O2

Selected Animations:

Collaboration with Scientific Publishers, Foundations and Patient organizations

10 Universities:

5 Publishers:

15+ Patient Organizations
and Foundations

Market-Leading
Visual Storytellers

6 animation types 

and 20 subtypes for every need — audience, company stage and budget.

The most advanced animation type on the market, based on computational biology methods. Science-grade molecular simulations for unprecedented accuracy.

Read more about the methods we use for this animation type in the whitepaper.

Featured:

Read more about the methods we use for this animation type in the whitepaper.

Featured:

Awarded:

Main 3D is the most universal animation type. It's scientifically rigorous, eye-catching, and very cinematic. It's a great match for most MoAs and MoDs for IR needs, alongside HCP communications.

The usual Main 3D animation type in combination with 2D elements. This is an excellent option for MoAs where there's a need to incorporate research data, schematics, or other additional information.

A relatively simple, yet still eye-catching 2D animation style is an ideal option for explainer animations, platform or AI-based technologies, alongside cases where IP details must not be disclosed.

Clear, simple, a eye-catching 2D animation style is an ideal option
for explainer animations, HCP and patient education videos

Clear, simple, a eye-catching 2D animation style is an ideal option
for explainer animations, HCP and patient education videos

This type is designed specifically for projects with tight deadlines. Through optimization, we achieve a rapid turnaround without compromising quality or scientific accuracy. The fastest type of 3D animation to produce on the market. 

A unique combination of scientific-grade molecular simulations that accurately represents real molecular interactions and states, with all the benefits of 2D animation —affordable and fast to produce. Unbeatable quality-to-cost-per-second ratio.  

Animation type:
Clinical trial update

Time:

1 week

Client:

Undisclosed

Education & Impact: 500M+ views

The Most Tech Enabled

3D type

High-end 3D

Deck3D

2D type

Pathway3D

+20 subtypes

7-8 weeks

8-10 weeks

4-5 weeks

3-5 weeks

10 days

1-9 weeks

In-House
Studio

All fueled by the most advanced production pipeline in the industry

Flexible & Modular Approach for Blexi

Confidential — Not for Public Consumption or Distribution

The "build your own" system provides complete transparency and flexibility in the planning phase, allowing tailoring to specific needs, audience, and budget.

Initial "chapterized" scripts and pricing for Blexi MOA provided under separate cover based on preliminary options below. Additional animation styles/options can be tailored further with additional discovery.

Pathway 3D

2D or Patient 2D

Deck 3D

Main 3D

Main 3D

Main 3D + 2D

High-end 3D

High-end 3D

Main 3D

* Initial "chapterized" scripts and pricing options for Blexi MOA provided under separate cover and can be tailored further.

Development of 1 infographic leave behind for multichannel use:

Hours and OOPs assume Visual Science to:

• ​Development of a front back leave behind for multichannel use

• Utilize existing JNJ Medical look/feel to develop layout

• Content and imagery leveraged from video animation

  • Introduction to AML

  • Mutations in develpment of AML

  • KMT2A in AML

  • NMP1 in AML

  • Mennin as a druggable target in AML

  • Menin inhibitors and advantages of Bleximenib

• Includes full editorial QC (copyedit, annotation and fact check) prior to each Med/Legal review

• Client reviews assume 3 rounds of client revisions (1 round for outline review, 1 prior to submission of layout for MLR review, 1 round prior to final MLR approval). Visual Science to prepare for 2 rounds of Med/Legal submission; 1 for review for revisions; BGB to upload into Veeva for final approval

• OOP Assumptions assume art usage rights, artist illustration, and retouching.

Price range: $25-$30k

Confidential — Not for Public Consumption or Distribution

Relevant Work Sample

Front 

Back

Strategic Services for Blexi

SCIENTIFIC NARRATIVES, PLATFORMS,  LEXICON DEVELOPMENT

• A medical strategic team that has developed
  100+ narratives and scientific platforms

• Expertise spanning early pipeline programs
  to blockbuster therapies

01

02

03

Confidential — Not for Public Consumption or Distribution

Program development:

Confidential — Not for Public Consumption or Distribution

01

02

03

Confidential — Not for Public Consumption or Distribution

Expert Insights

Deliverable

Slide set in PPT including results from audit,
high-level narrative and key data gaps
(up to 40 slides)

Workshops

Evidence

Early clinical data, Data on file (DOF),
competitive data

Current asset data, competitive
data included as bibilography

Current asset data, competitive data, fully
annoted/referenced, and key evidence gaps

Scientific Debrief only

Virtual workshop up to 2 hours and summary of key
findings in PPT (8-10 slides)

1/2 Day workshop with up to 5-7 key
company stakeholders; Summary of key
decisions in PPT (15-20 slides)

Incorporate secondary market research
and/or expert feedback captured via AdBds
or Investigators Meetings

Conduct 1-2 one-hour Expert Interviews
and incorporate feedback

Workshop with 3-5 Experts;
remote meeting up to 2 hours

Slide set in PPT including results from audit,
high-level narrative and key data gaps
(up to 15 slides)

Online Scientific Platform with access
for multiple stakeholders

Narrative/Platform
and Lexicon

Generate high-level narrative focused on unmet
needs in disease state, key differentiating features
of the asset

Narrative and Platform initiation, including
level 1 core concepts; Level 2 Scientific statements;
placeholders for key evidence needed

Full Scientific Platform including Narrative Level 1,
Scientific Statements Level 2, and Key pieces
of evidence Level 3

Asset 1

Landscape assessment, review of pre-clinical
or early stage data, competitive assesment

Landscape assessment, competitive assessment,
market research, Add summaries,
and medical download call

Landscape assessment, competitive assessment,
market research, AdBd summaries, and medical
download call; 5-7 slide summary of audit

Early Stage (Clin-P1)

Mid Stage (P1-P2)

Late Stage (P2-Pre-Launch)

Timing
kickoff to delivery

8-10 weeks

4-6 Weeks

12-15 weeks

Ballpark
fees only

$80-100K

$45-65K

$120-150K

Partnering

Your Visual Science Team*

Sean Rooney, PhD

Chief Medical Strategy

Chief Executive Officer

Michael Russo

Head, Strategic Partnerships

Ivan K., M.Sc

Jenn Terrell, MBA

Client Services Lead

Yury Stefanov, PhD

Nancy Miller

Marianna Jain

Associate Director,
Project Management

Lori Magnelli

VP, Managomant
Supervisor

Marni Kelman. M.Sc

Rich Friel

Lori Magnelli

Associate Project
Manager

Nicole Cooper

Dan Purkis

Qais Saket

Medical Writer

Medical Writer

Medical Writer

Medical Writer

Chief Science Offer

Medical Doctor

Associate Medical
Director

Max Kulemza

Head of CG & Tech

Tobias Van Schnider

VP, IT

Additional support resources (Editorial, Studio, Digital, Production, Presentation Services) are available to meet your needs

Alex Whitewood

VP, Creative Director

Ihor Cherno

VP, VFX

Nicole Cooper

Associate Medical
Director

Appendix

DECKS AND INFOGRAPHICS

97% of clients rate working with us 9 or 10/10

Type:
Series B deck

Time:

6 weeks

Scope:

IR, scientific flow optimization, design, illustrations, animations
 

Type:
Corporate deck  for public company

Time:

4 weeks

Scope:

Design, illustrations, animations
 

Type:
Corporate deck  for public company

Time:

5 weeks

Scope:

Scientific flow optimization, design, illustrations, animations
 

Type:
High-end 3D infographics for deck

Time:

1 week

Type:
2D infographics for deck

Time:

1 week

WEB & APPS

97% of clients rate working with us 9 or 10/10

Type:
Corporate website for public company

Time:

10 weeks

Scope:

Design, development, illustrations, animations
 

Type:
Corporate website for public company

Time:

9 weeks

Scope:

Design, development, illustrations, animations
 

POSTER AR 

97% of clients rate working with us 9 or 10/10

Client Testimonials

97% of clients rate working with us 9 or 10/10

Have we piqued your interest? Let's chat.